At a very early stage of the cardiometabolic
continuum, sympathetic overdrive is often
associated with a cardiovascular risk factors which
can increase in intensity and trigger a complication
which finally can lead to the installation of a
chronic cardiometabolic disease.

Sympathetic overdrive is a common thread
between: hypertension, CHD, and heart failure.

Throughout the ages, man has suffered from a
carry-on effect of sympathetic overdrive. His
cardiovascular system memorizes the burden he is
going through at every step of the disease,
building year over year the memory of the heart.